J,
All parts for the '78 to '80 CR250 bottom ends are pretty much interchangeable; however, there are several parts that were upgraded from year to year; the most noticeable would be the cases. The '78 cases lacked a shield behind the clutch lifter area (in front of the counter shaft) to protect the lifter recess when the chain gets tossed. Both the '78 and '79 left case halves lacked the three vertical support webbings at the area of the left transfers; which provide support to the base gasket area. And of course, everyone knows about the kick start pinion, clutch basket and ignition.
I'd think a really hot setup for the '80 CR250RA would be the "E" stator and CDI, the Pro-Form Mugen pipe and the Mugen ME250 Pro cylinder...I think that would be an interesting '80 bike to ride. I plan on trying the "E" setup on my '80 ME360, see if that will make it rev like my 125's.
Take care,
Robbie